The association of food consumption and nutrient intake with endometriosis risk in Iranian women: A case-control study|
Youseflu, Samaneh; Sadatmahalleh, Shahideh Jahanian; Mottaghi, Azadeh & Kazemnejad, Anoshirvan
Background: Endometriosis, defined as the attendance of endometrial-like lesions in
extra uterine locations, causes pain, infertility, and reduced quality of life.
Objective: To evaluate the relationship between food consumption and nutrient intake
with risk of endometriosis.
Materials and Methods: Of the 156 women approached for the study, 78 women had
endometriosis and 78 healthy women were included in the control group. Dietary
data were collected using a validated 147-item semi-quantitative Food Frequency
Questionnaire (FFQ) with the standard serving size. A logistic regression model was
used to determine the association of macronutrients and energy intake with the risk of
Results: In women with higher intake of protein, especially animal protein,
monounsaturated fatty acids, soluble and insoluble fiber, oleic acid, eicosapentaenoic
acid, and docosahexaenoic acid endometriosis is less common (p < 0.05). High
consumption of vegetables, fruits, red meat, yellow vegetables, potatoes, legumes,
dairy products, liquid oil, and low intake of fried potatoes was associated with a lower
risk of endometriosis (p < 0.05).
Conclusion: Regarding the association of dietary intake on endometriosis risk,
counseling about improving the dietary structure can contribute toward the prevention
and control of endometriosis.
Endometriosis; Macronutrient; Diet; Case-control study.