Comparison of serum level of some trace elements and vitamin D between patients with premenstrual syndrome and normal controls: A cross-sectional study|
Fatemi, Mahnoosh; Allahdadian, Maryam & Bahadorani, Mehrnoosh
Background: Premenstrual syndrome (PMS) is a common problem among women and
is identified by reversal emotional, psychological, and physical signs during the luteal
phase. These signs, however, lower down in the follicular phase. The cause of PMS
isn’t very well-known up to nowControl group and many researchers have suggested
that mineral compounds and vitamins can inhibit these symptoms.
Objective: The objective of this study is to compare the serum level of some trace
elements and vitamin D between normal controls and patients with PMS.
Materials and Methods: 300 female students (19–21 yr old) from Falavarjan County
were randomly selected and asked to complete a standard questionnaire on PMS
during three menstruation cycles. The students were divided into two groups: healthy
persons (control) and PMS persons, and PMS was determined on the basis of
the answers to the questionnaire. Thereafter, the serum concentrations of zinc,
iron, calcium, magnesium, potassium, sodium, and Vitamin D3 were measured and
compared between the two groups.
Results: Our results showed that the PMS prevalence was about 41.5%. The level
of vitamin D decreased in both the control and PMS groups, with a significantly lower
range of vitamin D (p ≤ 0.05) in the PMS group. Other factors had no significant change
between the two groups.
Conclusion: Vitamin D deficiency was probably one of the most important causes of
unpleasant symptoms of PMS between these students.
Premenstrual syndrome; Trace elements; Vitamin D.