International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 17, No. 8, 2019, pp. 551-556
Bioline Code: rm19059
Full paper language: English
Document type: Research Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 17, No. 8, 2019, pp. 551-556
© Copyright 2019 - Sana Karamolahi et al.
Impact of hepatitis B virus and hepatitis C virus infection on sperm parameters of infertile men|
Karamolahi, Sana; Yazdi, Reza Salman; Zangeneh, Mehrangiz; Makiani, Mahin Jamshidi; Farhoodi, Behnam & Gilani, Mohammad Ali Sedighi
Background: Viral hepatitis is one of the health problems which have the effects on the
health issues. It seems that hepatitis B virus (HBV) and hepatitis C virus (HCV) infection
have negative impacts on the semen quality and male infertility rate.
Objective: In this study, we aimed to evaluate the effects of HBV and HCV on
sperm quality among Iranian infertile men referred to Royan Institute Reproductive
Biomedicine Research Center between 2003 and 2014.
Materials and Methods: This retrospective case-control study included 112 HBV
positive infertile men and 47 HCV positive infertile men as case group and 112 HBV
negative andHCVnegative matched infertile men as a control group. All semen analysis
and viral parameters assessment was performed in the central laboratory with the same
method and instruments.
Results: Sperm count among infertile men with HBV and HCV infection was significantly
lower than control group [the mean of the total sperm count 100.95 ± 118.59,
118.22 ± 141.18, 166.27 ± 151.25 (p < 0.001)]. Sperm motility was significantly decreased
in HBV and HCV positive men in comparison to the control group [30.97 ± 25.88,
31.09 ± 28.72, 40.87 ± 23.37, respectively (p < 0.007)]. The percentage of normal sperm
morphology was significantly higher in control group in comparison to HBV and HCV
infected group [the mean of the normal semen morphology 3.23 ± 3.27, 3.70 ± 3.83,
4.51 ± 3.15 p < 0.015]. Although there is a significant decline in liquefaction time in the
case group but the viscosity, semen volume, and PH of semen samples were similar in
the both case and control groups.
Conclusion: Our results suggest that HBV and HCV infection are associated with poor
Hepatitis B virus; Hepatitis C virus; Male; Infertility; Sperm.
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