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International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433
EISSN: 2008-2177
Vol. 17, No. 8, 2019, pp. 533-542
Bioline Code: rm19057
Full paper language: English
Document type: Review Article
Document available free of charge

International Journal of Reproductive BioMedicine, Vol. 17, No. 8, 2019, pp. 533-542

 en The prevalence of polycystic ovary syndrome in adolescents: A systematic review and meta-analysis
Naz, Marzieh Saei Ghare; Tehrani, Fahimeh Ramezani; Majd, Hamid Alavi; Ahmadi, Fazlollah; Ozgoli, Giti; Fakari, Farzaneh Rashidi & Ghasemi, Vida

Abstract

Background: Polycystic ovarian syndrome is an endocrine disorder with many complications. This syndrome is a growing concern among adolescents around the world, with varying reports of its prevalence in different parts of the world.
Objective: This study aimed to determine the prevalence of polycystic ovary syndrome in adolescents by a systematic review and meta-analysis.
Materials and Methods: In this study, a search for published articles with an English language limitation and without a time limit was done in different databases (Scopus, PubMed, and Web of Science, Emabse and Cochrane) in January 2019. The 12 studies that met the criteria for entering a qualitative assessment scale of 5 and higher were subjected to systematic review and meta-analysis. Egger and Begg’s tests were used to check the publication bias. Data were analyzed with STATA software, version 11.1.
Results: Twelve studies were included for meta-analysis. The total number of participants in the study was 149,477. The average quality score of all studies was 8.67 (range: 5–10). The prevalence of polycystic ovarian syndrome in adolescents based on the Rotterdam criteria was 11.04% (95% CI: 6.84–16.09%), based on the National Institute of Health criteria, it was 3.39% (95% CI: 0.28–9.54%), and based on Androgen Excess and Polycystic Ovary Syndrome Society, it was 8.03% (95% CI: 6.24–10.01%)
Conclusion: The result of this study showed that there is a variation in the prevalence of PCOS in adolescents based on different criteria; we suggest more community-based studies among adolescences in different parts of the world.

Keywords
Polycystic ovary syndrome; Prevalence; Meta-analysis; Adolescence.

 
© Copyright 2019 - Marzieh Saei Ghare Naz et al.
Alternative site location: http://www.ijrm.ir

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