The relationship between body mass index and preeclampsia: A systematic review and meta-analysis|
Motedayen, Morteza; Rafiei, Mohammad; Tavirani, Mostafa Rezaei; Sayehmiri, Kourosh & Dousti, Majid
Background: One of the causes of maternal and fetal mortality and morbidity is
pregnancy-induced hypertension, the most common form of which is preeclampsia that
causes many complications for mother and fetus.
Objective: The aim of this systematic review and meta-analysis was to determine the
relationship between body mass index (BMI) and preeclampsia in Iran.
Materials and Methods: Using valid keywords in the SID database, PubMed, Scopus,
data obtained from all the articles, which were reviewed in Iran between 2000 and
2016, were combined using the meta-analysis method (random-effects model) and
analyzed using STATA version 11.1.
Results: A total number of 5,946 samples were enrolled in 16 studies with the mean BMI
values of 25.13, 27.42, and 26.33 kg /m2 in the healthy, mild, and severe preeclamptic
Conclusion: The results of this study revealed that there is a significant relationship
between BMI and the risk of preeclampsia, so it can be said that BMI may be one of
the ways to diagnose preeclampsia.
Preeclampsia; Body mass index; Iran; Meta-analysis.