International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 16, No. 11, 2018, pp. 719-722
Bioline Code: rm18088
Full paper language: English
Document type: Short Communication
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 16, No. 11, 2018, pp. 719-722
© Copyright 2018 - International Journal of Reproductive BioMedicine
Investigation of anti-mullerian hormone (AMH) level and ovarian response in infertile women with endometriosis in IVF cycles|
Safdarian, Leili; Attar, Seyedeh Noushin Ghalandarpoor; Aleyasin, Ashraf; Aghahosseini, Marzieh; Sarfjoo, Fateme Sadaf & Hosseinimousa, Sedigheh
Background: Endometriosis, can cause ovarian conflict and reduced ovarian reserve
that could lead to lower response to assisted reproductive techniques
Objective: Current study was conducted to determine the association between level
of anti-mullerian hormone (AMH) and the infertility treatment outcomes in infertile
females with endometriosis versus the non-endometriosis infertile subject.
Materials and Methods: In this case-control study, 64 infertile females who
referred to Shariati Hospital from April 2015 to November 2017 were enrolled. They
were divided in two groups of 32 patients (endometriosis and non-endometriosis
women). The anti-mullerian hormone level among all subjects was determined,
treatment outcomes were evaluated and association between these factors was
Results: It was seen that the anti-mullerian hormone (p=0.06), the number of
retrieved oocytes (p=0.7) and embryos (p=0.7), implantation rate (p=0.6) and
clinical pregnancy rate (p=0.9) were similar between two groups. In patients with
stage 3 or 4 endometriosis who had lower serum AMH level significantly (p=0.001)
less oocytes were retrieved (p=0.001) and less transferrable embryos (p=0.03) were
achieved. However, implantation and pregnancy rates did not differ (p=0.7) (p=0.6).
Conclusion: Totally, according to the obtained results, it may be concluded that
ovarian reserve has more significant role in predicting infertility treatment outcome
rather than receptive endometrium.
Endometriosis; Infertility; Anti-mullerian hormone.
Alternative site location: http://www.ijrm.ir