International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 16, No. 11, 2018, pp. 697-702
Bioline Code: rm18085
Full paper language: English
Document type: Research Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 16, No. 11, 2018, pp. 697-702
© Copyright 2018 - International Journal of Reproductive BioMedicine
The effect of inflammatory diseases associated with opportunistic urogenital infection on the hormonal function of the female reproductive system|
Rasimovich, Abdrakhmanov Azat & Mindrakhmanovich, Abdrakhmanov Rasim
Background: Sexually transmitted infections play a great role in formation of
inflammatory diseases of female urogenital system. These diseases can cause a
decrease in the level of female sex hormones, as well as the ratio of estrogens and
Objective: To determine changes in the state of sex hormones in women with
inflammatory diseases of ovaries associated with opportunistic urogenital flora.
Materials and Methods: 136 women aged 18-39 yr participated in this cross-sectional
clinical study. They were examined with the use of a complex of clinical,
laboratory and instrumental methods of examination. The patients with confirmed
diagnosis of inflammatory disease of reproductive system associated with
opportunistic urogenital infection have been under blood analysis to reveal the
concentration of follicle-stimulating hormone, luteinizing hormone, and estrogens.
Results: After the treatment the functional capacity of ovary significantly increased,
proved by a corresponding increase in the concentration of estradiol hormone in
blood serum in all phases of menstrual cycle. According to estradiol in follicular
phase its concentration was increased from 421.8±10.8 nmol/L to 581.3±10.2
nmol/L. The elevation in the ratio of estradiol/testosterone hormones in blood serum
also is demonstrated.
Conclusion: Inflammatory diseases associated with opportunistic urogenital
infection is responsible for a decrease of female sex hormones and the ratio of
estrogens and androgens.
Urogenital infection; Pelvic inflammatory disease; Reproductive system; Estradiol; Infertility.
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