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International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433
EISSN: 2008-2177
Vol. 16, No. 6, 2018, pp. 413-416
Bioline Code: rm18047
Full paper language: English
Document type: Case Report
Document available free of charge

International Journal of Reproductive BioMedicine, Vol. 16, No. 6, 2018, pp. 413-416

 en Adnexal mass with extremely high levels of CA-125 and CA19-9 but normal Human Epididymis Protein 4 (HE4) and Risk of Ovarian Malignancy Algorithm (ROMA): Endometriosis or ovarian malignancy? A case report
Khodaverdi, Sepideh; Amini-Moghaddam, Soheila; Nokiani, Fariba Almassi; Hashemi, Neda & Beigi, Robabeh Mohammad


Background: It has been shown that Carbohydrate antigen (CA) 125 and CA 19-9 tumor markers are useful for diagnosis and follow up of ovarian carcinoma.
Case: In this case, we reported the high level of CA-125 and CA 19-9 with large right ovarian intact endometrioma and extensive involvement of omentum.
Conclusion: Human Epididymis protein (HE4) and Risk of ovarian malignancy algorithm (ROMA) can be useful in differentiation between malignancies and benign pathologies with a good sensitivity and specificity value.

Human epididymis protein 4 (HE4); Risk of ovarian malignancy algorithm (ROMA).

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