International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 16, No. 2, 2018, pp. 109-114
Bioline Code: rm18014
Full paper language: English
Document type: Research Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 16, No. 2, 2018, pp. 109-114
© Copyright 2018 - International Journal of Reproductive BioMedicine
Maternal history and uterine artery wave form in the prediction of early-onset and late-onset preeclampsia: A cohort study|
Sharma, Nidhi; Jayashree, Krishnamurthy & Nadhamuni, Kulasekaran
Background: Pregnancy induced hypertension (PIH) is a significant cause of
maternal morbidity and mortality. Pregnancy-induced-hypertension can be
prevented by identification of prenatal and antenatal factors. The uterine artery
Doppler waveform transforms into a high flow with low resistance at 22-24 wk.
Objective: To study the maternal risk factors and uterine artery Doppler waveform
in singleton mid-trimester pregnancy and predict the occurrence of pregnancy-induced
Materials and Methods: This is a cohort study comprising of Doppler ultrasound
examination of the uterine arteries at 20-23 wk gestation in 697 women with
singleton pregnancies attending a routine target scan. The pregnant women were
followed up. PIH was recorded in 57 (8.18%) of all pregnancies.
Results: Maternal age >34 yr, primiparity, the presence of chronic hypertension was
also associated with increased risk of PIH. High pulsatility index (>95th percentile)
as compared to low pulsatility index was a good tool for the detection of PIH
(sensitivity 91.23% and specificity 99.06%, p<0.05). Presence of high pulsatility
was a significant risk factor for early-onset PIH as compared to late-onset PIH.
Conclusion: Uterine artery Doppler can be safely performed at the time of routine
target anomaly scan in the second trimester. It is simple, economical, feasible and
with good detection rates.
Hypertension; Preeclampsia; Trophoblasts; Ultrasonography; Doppler; Uterine artery.
Alternative site location: http://www.ijrm.ir