International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 15, No. 11, 2017, pp. 729-734
Bioline Code: rm17085
Full paper language: English
Document type: Research Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 15, No. 11, 2017, pp. 729-734
© Copyright 2017 - International Journal of Reproductive BioMedicine
Cervical gland area as an ultrasound marker for prediction of preterm delivery: A cohort study|
Marsoosi, Vajiheh; Pirjani, Reihaneh; Jafarabadi, Mohamad Asghari; Mashhadian, Mina; Ziaee, Saeedeh & Moini, Ashraf
Background: Preterm labor is a major cause of perinatal morbidity and mortality
and it might be predicted by assessing the cervical change.
Objective: To assess the association between absence of cervical gland area (CGA)
and spontaneous preterm labor (SPTL).
Materials and Methods: This prospective cohort study was performed on 200
singleton pregnant women with a history of SPTL, second-trimester abortion in the
previous pregnancy or lower abdominal pain in current pregnancy. Each patient
underwent one transvaginal ultrasound examination between 14-28 wk of gestation.
Cervical length was measured and CGA was identified and their relationship with
SPTL before 35 and 37 wk gestation was evaluated using STATA software version
Results: The mean of cervical length was 36.5 mm (SD=8.4), the shortest
measurement was 9 mm, and the longest one was 61 mm. Short cervical length
(≤18mm) was significantly associated with SPTL before 35 and 37 wk gestation.
Cervical gland area (the hypoechogenic or echogenic area around the cervical canal)
was present in 189 (94.5%) patients. Absent of CGA had a significant relationship
with SPTL before 35 and 37 wk gestation (p=0.01 and p<0.001, respectively).
Cervical length was shorter in women with absent CGA in comparison with subjects
with present CGA: 37±10 mm in CGA present group and 23±9 mm in CGA absent
Conclusion: Our study showed that cervical gland area might be an important
predictor of SPTL which should be confirmed with further researches.
Labor; Preterm; Ultrasonography; Cervical length measurement; Pregnancy outcome.
Alternative site location: http://www.ijrm.ir