Prevalence of premenstrual syndrome in Iran: A systematic review and meta-analysis|
Ranjbaran, Mehdi; Samani, Reza Omani; Almasi-Hashiani, Amir; Matourypour, Pegah & Moini, Ashraf
Background: Premenstrual syndrome (PMS) is a common disorder characterized by
physical, mental and behavioral changes in the luteal phase of the menstrual cycle in
the reproductive age women.
Objective: The present study aimed to determine the overall prevalence of PMS in
Iran by a systematic review and meta-analysis study.
Materials and Methods: In this systematic review and meta-analysis, we searched
international databases included ISI Web of Knowledge, PubMed/Medline, Scopus,
Google Scholar, and also local databases including Iranmedex, Scientific
Information Database, and Magiran for articles in English and Persian language
published up to September 2016. We carried out data analysis with Stata version 11.
We examined heterogeneity in the results of studies through I2 statistics and Chi-square
based Q test. Also, we investigated the effects of potential heterogeneity
factors in the prevalence of PMS by meta-regression.
Results: We studied a total of 9147 reproductive-age women from 24 articles which
entered to meta-analysis. Based on the result of random effect model, we estimated
the overall prevalence of PMS 70.8% [95% CI: 63.8-77.7]. The results of subgroup
analysis revealed that prevalence of PMS was 80.4% (95% CI; 66.9-93.9) among
high school students, 68.9% (95% CI; 59.2-78.6) among university students, and
54.9% (95% CI; 51.6-58.2) in general population. Univariate meta-regression model
showed that prevalence of PMS was decreased by increasing the age of subjects but
this was not statistically significant (p=0.155).
Conclusion: Our finding showed that PMS was prevalent in Iranian reproductive
age women especially among high school students. More epidemiological research
for determining factors that affect PMS prevalence seems essential.
Premenstrual syndrome; Iran; Systematic review; Meta-analysis.