International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 15, No. 10, 2017, pp. 613-618
Bioline Code: rm17072
Full paper language: English
Document type: Research Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 15, No. 10, 2017, pp. 613-618
© Copyright 2017 - International Journal of Reproductive BioMedicine
The prevalence of, and risk factors for, mycoplasma genitalium infection among infertile women in Ibadan: A cross-sectional study|
Ajani, Tinuade Adesola; Oluwasola, Timothy A. Olusesan; Ajani, Mustapha A. & Bakare, Rasheed Ajani
Background: The association of mycoplasma genitalium (M. genitalium) with
infertility has been documented. The infections are asymptomatic and difficult to
diagnose. Understanding the associated risk factors will help in facilitating better
screening measures for at-risk groups.
Objective: The aim was to determine the prevalence of, and risk factors for, M.
genitalium infection among infertile women in Ibadan.
Materials and Methods: In this cross-sectional study, 402 women (267 infertile
and 135 fertile) referred to 2 hospitals in Ibadan between March and November 2015
were enrolled. Information was obtained, using structured questionnaire, on
sociodemographic and behavioral characteristics of the respondents while
endocervical swabs were obtained for detection of M. genitalium. MgPa gene was
diagnosed using the conventional Polymerase chain reaction. Bands corresponding
to 495kb were documented as positive for M. genitalium.
Results: Among the infertile women, 43 (16.1%) had evidence of M. genitalium
infection as against 3 (2.2%) of women without infertility (p<0.001). Associated risk
factors included having more than one lifetime sexual partner (OR=10.13, 95% CI:
3.76-33.97); husbands having other sexual partners (OR=12.88, 95% CI: 2.08-90.63); being a serial monogamist (OR=6, 95% CI: 4.35-8.27) and low socioeconomic
status (OR=2.80, 95% CI: 1.28-6.10). No relationship exists between the
previous history of sexually transmitted infections and M. genitalium.
Conclusion: The risk factors for M. genitalium infection are similar to those
peculiar to other sexually transmitted infections. Its routine screening should be
incorporated into the current protocol for microbiological evaluation of infertile
Infertility; Mycoplasma genitalium; Prevalence; Risk factors; Screening.
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