International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 15, No. 10, 2017, pp. 601-612
Bioline Code: rm17071
Full paper language: English
Document type: Review Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 15, No. 10, 2017, pp. 601-612
© Copyright 2017 - International Journal of Reproductive BioMedicine
Reconstruction of mammalian oocytes by germinal vesicle transfer: A systematic review|
Darbandi, Sara; Darbandi, Mahsa; Khorshid, Hamid Reza Khorram; Shirazi, Abolfazl; Sadeghi, Mohammad Reza; Agarwal, Ashok; Hasani, Safaa Al-; Naderi, Mohammad Mehdi; Ayaz, Ahmet & Akhondi, Mohammad Mehdi
Nuclear transfer procedures have been recently applied for clinical and research
targets as a novel assisted reproductive technique and were used for increasing the
oocyte activity during its growth and maturation. In this review, we summarized the
nuclear transfer technique for germinal vesicle stage oocytes to reconstruct the
maturation of them. Our study covered publications between 1966 and August 2017.
In result utilized germinal vesicle transfer techniques, fusion, and fertilization
survival rate on five different mammalian species are discussed, regarding their
potential clinical application. It seems that with a study on this method, there is real
hope for effective treatments of old oocytes or oocytes containing mitochondrial
problems in the near future.
Germinal vesicle; Micromanipulation; Nuclear transfer; Oocyte.
Alternative site location: http://www.ijrm.ir