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International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433
EISSN: 2008-2177
Vol. 15, No. 10, 2017, pp. 601-612
Bioline Code: rm17071
Full paper language: English
Document type: Review Article
Document available free of charge

International Journal of Reproductive BioMedicine, Vol. 15, No. 10, 2017, pp. 601-612

 en Reconstruction of mammalian oocytes by germinal vesicle transfer: A systematic review
Darbandi, Sara; Darbandi, Mahsa; Khorshid, Hamid Reza Khorram; Shirazi, Abolfazl; Sadeghi, Mohammad Reza; Agarwal, Ashok; Hasani, Safaa Al-; Naderi, Mohammad Mehdi; Ayaz, Ahmet & Akhondi, Mohammad Mehdi

Abstract

Nuclear transfer procedures have been recently applied for clinical and research targets as a novel assisted reproductive technique and were used for increasing the oocyte activity during its growth and maturation. In this review, we summarized the nuclear transfer technique for germinal vesicle stage oocytes to reconstruct the maturation of them. Our study covered publications between 1966 and August 2017. In result utilized germinal vesicle transfer techniques, fusion, and fertilization survival rate on five different mammalian species are discussed, regarding their potential clinical application. It seems that with a study on this method, there is real hope for effective treatments of old oocytes or oocytes containing mitochondrial problems in the near future.

Keywords
Germinal vesicle; Micromanipulation; Nuclear transfer; Oocyte.

 
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Alternative site location: http://www.ijrm.ir

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