International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 15, No. 5, 2017, pp. 305-310
Bioline Code: rm17041
Full paper language: English
Document type: Research Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 15, No. 5, 2017, pp. 305-310
© Copyright 2017 - International Journal of Reproductive Medicine
Relative frequency of human papillomavirus genotypes and related sociodemographic characteristics in women referred to a general hospital in Tehran, 2014- 2015: A cross-sectional study|
Makiani, Mahin Jamshidi; Minaeian, Sara; Moghaddam, Soheila Amini; Moosavi, Seyed Akbar; Moeini, Zahra; Zamani, Vajihe; Sabbagh, Mahnaz Karbalaei & Forghani, Hosein
Background: Human papilloma virus (HPV) is one of the major public health
problems and the main causes of cervical cancer. The prevalence HPV infection in
developing countries with low financial resources is high.
Objective: This study aimed to determine the relative frequency of HPV genotypes
and its sociodemographic characteristics in women referred to a general hospital in
Tehran, Iran from 2014-2015.
Materials and Methods: This cross-sectional study was performed in 400 women
with Pap smear samples, referring to to a general hospital in Tehran, Iran from 2014-2015. The detection of 28 HPV genotypes was performed by using the Multiplex
PCR technique. The sociodemographic survey was conducted for each HPV positive
Results: HPV-positive infection was detected in 155 (38.75%) women aged 17-85
years. HPV 16 (19.1%) was the most prevalent type, followed by HPV 39 (12.5%)
and HPV 18 (8.9%). The highest rate of HPV infection was observed at the age of
36 years (7.7%). The level of education and economic situation of each woman were
showed most of HPV-positive women had a high school diploma (34.6%) and
average economic situation (67,9%). 60.9% of these women were a housewife, and
67.3% lived in the capital .
Conclusion: Determination of HPV genotype and risk factor related to HPV
infection in each geographical region can lead to the production of effective
vaccines against the HPV virus. It can also be useful for disease management and
high sensitivity diagnosis of cervical intraepithelial neoplasia.
Human papilloma virus; Frequency; Multiplex PCR; Socioeconomic factors.
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