About Bioline  All Journals  Testimonials  Membership  News  Donations

International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433
EISSN: 2008-2177
Vol. 14, No. 11, 2016, pp. 709-712
Bioline Code: rm16092
Full paper language: English
Document type: Research Article
Document available free of charge

International Journal of Reproductive BioMedicine, Vol. 14, No. 11, 2016, pp. 709-712

 en Assessing the efficacy of vaginal hyoscine butyl bromide on cervical ripening prior to intrauterine procedures: A double-blinded clinical trial
Hadadian, Shiva & Fallahian, Masoumeh


Background: Unripe cervix prevents entering the endometrial cavity during intrauterine procedures. Mechanical dilatation of cervical canal might cause undesirable complications.
Objective: To investigate the substitute of mechanical intervention with chemical treatment by administering hyoscine to patients.
Materials and Methods: Sixty non-pregnant women, 20-70 years of age, with a closed cervix who were scheduled for an intrauterine procedure, were randomly divided into two groups. Group A as experimental (received two doses of hyoscine) and group B, as control group (received two doses of vitamin B6) in the vagina (8 hrs and 2 hrs before procedure) and the effect of these two drugs on dilatation and consistency of cervix were studied56T.
Results: Statistics resulted from Mann-Whitney U test (p=0.027) and χ2(p=0.002) indicated that in premenopausal women, the priming effect of hyoscine on dilatation and consistency of uterine cervix was significant, but there were no significant benefits from giving vaginal hyoscine to menopausal women preoperatively (p=0.603).
Conclusion: Hyoscine proved a good choice for inducing cervical priming before intrauterine procedures in premenopausal women.

Butylscopolammonium bromide; Cervical dilatation; Cervical ripening

© Copyright 2016 - Iranian Journal of Reproductive Medicine
Alternative site location:

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2020, Site last up-dated on 10-Sep-2020.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil