International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 10, No. 6, 2012, pp. 567-570
Bioline Code: rm12082
Full paper language: English
Document type: Research Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 10, No. 6, 2012, pp. 567-570
© Copyright 2012 - Iranian Journal of Reproductive Medicine
Efficacy of the local endometrial injury in patients who had previous failed IVF-ICSI outcome|
Kara, Mustafa; Aydin, Turgut; Turktekin, Nurettin & S., Karacavus
Background: The latest studies reported that local endometrial injury is a useful method to improve the success of IVF-ICSI outcome.
Objective: To assess whether local endometrial injury occurred by Pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent IVF-ICSI cycle in patients who had recurrent IVF failure.
Materials and Methods: An endometrial biopsy was performed on day 21st in 41 patients as intervention group in this retrospective cross-sectional study. The control group contained 42 women.
Results: Implantation rate was 22.5% and 10.5% in intervention and control group, respectively and this difference was found to be statistically significant (p=001). Pregnancy rate was 43.9% in the intervention group and this parameter was significantly lower in control group (21.4%) (p=0.03).
Conclusion: Local endometrial injury in the nontransfer cycle increases the implantation rate and pregnancy rate in the subsequent IVF-ICSI cycle in patients who had previous failed IVF-ICSI outcome.
Local endometrial injury, In vitro fertilization, Embryo transfer, Pregnancy.
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