International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
Vol. 6, No. 2, 2008, pp. 95-100
Bioline Code: rm08016
Full paper language: English
Document type: Research Article
Document available free of charge
International Journal of Reproductive BioMedicine, Vol. 6, No. 2, 2008, pp. 95-100
© Copyright 2008 - Iranian Journal of Reproductive Medicine
Conservative management in young patients with borderline and malignant ovarian tumors: outcomes and pregnancies|
Ghaemmaghami, Fatemeh; Zarchi, Mojgan Karimi; Naseri, Azita; Mousavi, Azam Sadat; Gilani, Mitra Modarres & Ramezanzadeh, Fatemeh
Recent studies have showed conservative management in selective
patients with borderline and malignant ovarian tumors is safe; therefore this management
is considered in patients with ovarian tumor who desire to preserve fertility.
This study has been performed to evaluate the clinical outcome and fertility in
patients with ovarian tumors who were treated conservatively.
Materials and Methods:
All patients who were treated conservatively (preservation of
uterus and at least one ovary) or were on follow-up and had recurrence were evaluated in
Vali-e-Asr Hospital during 2000-2004.
Among 410 patients with ovarian tumors, 60 were treated conservatively. Age
range was 13-34 years. Twenty-six of patients (43.3%) were desired pregnancy and 34
(56%) patients did not. Three (5%) patients had history of infertility. Histological types of
tumors were as follows; 15(25%) borderline tumors, 10(16.7%) epithelial tumors,
26(43.3%) germ cell tumors, and 9(15%) sex cord tumors. Range of follow-up time was
12-48 months. Seven term pregnancies in 6 patients had been occurred, 1 in epithelial
group, 2 in germ cell group, 1 in sex cord group and 3 in borderline group. Nine patients
had recurrence and 2 patients expired, including one patient with serous cyst carcinoma
(Stage IIIC).This patient had refused radical surgery and referred to our center with
recurrence. Another patient had immature teratoma (Stage IIIC).
Conservative surgical management in young patients with stage I (grade 1,
2) of epithelial ovarian tumor and sex cord-stromal tumor and in patients with borderline
and germ cell ovarian tumors could be performed in order to preserve fertility.
Ovarian cancer, Conservative management, Fertility sparing surgery.
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